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Role of Akt Activation in PARP Inhibitor Resistance in Cancer
Poly(ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the therapy of several types of cancers not responding to conventional treatments. However, de novo and acquired PARP inhibitor resistance is a significant limiting factor in the clinical therapy, and the underlying mecha...
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| Publicado en: | Cancers (Basel) |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7139751/ https://ncbi.nlm.nih.gov/pubmed/32106627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030532 |
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