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Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand Activation

Receptor tyrosine kinases (RTKs) orchestrate cell motility and differentiation. Deregulated RTKs may promote cancer and are prime targets for specific inhibitors. Increasing evidence indicates that resistance to inhibitor treatment involves receptor cross-interactions circumventing inhibition of one...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Harwardt, Marie-Lena I.E., Schröder, Mark S., Li, Yunqing, Malkusch, Sebastian, Freund, Petra, Gupta, Shashi, Janjic, Nebojsa, Strauss, Sebastian, Jungmann, Ralf, Dietz, Marina S., Heilemann, Mike
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215329/
https://ncbi.nlm.nih.gov/pubmed/32316583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082803
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