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Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand Activation

Receptor tyrosine kinases (RTKs) orchestrate cell motility and differentiation. Deregulated RTKs may promote cancer and are prime targets for specific inhibitors. Increasing evidence indicates that resistance to inhibitor treatment involves receptor cross-interactions circumventing inhibition of one...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Harwardt, Marie-Lena I.E., Schröder, Mark S., Li, Yunqing, Malkusch, Sebastian, Freund, Petra, Gupta, Shashi, Janjic, Nebojsa, Strauss, Sebastian, Jungmann, Ralf, Dietz, Marina S., Heilemann, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215329/
https://ncbi.nlm.nih.gov/pubmed/32316583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082803
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