Down-Regulated Exosomal MicroRNA-221 – 3p Derived From Senescent Mesenchymal Stem Cells Impairs Heart Repair

The composition and biological activity of donor cells is largely determined by the exosomes they secrete. In this study, we isolated exosomes from young (Young-Exo) and aged (Age-Exo) mesenchymal stem cells (MSCs) and compared their regeneration activity. Young Exo MSCs were more efficient than Age...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Sun, Ling, Zhu, Wenwu, Zhao, Pengcheng, Zhang, Jian, Lu, Yao, Zhu, Yeqian, Zhao, Wei, Liu, Yaowu, Chen, Qiushi, Zhang, Fengxiang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214920/
https://ncbi.nlm.nih.gov/pubmed/32432109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00263
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