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Long noncoding RNA UCA1 from hypoxia-conditioned hMSC-derived exosomes: a novel molecular target for cardioprotection through miR-873-5p/XIAP axis

Exosomes (Exo) secreted from mesenchymal stem cells (hMSCs) are protective against myocardial injury. The purpose of the study was to investigate the role and mechanisms by which exosomes promote cardiomyocyte survival and function following myocardial infarction (MI). hMSCs were cultured under hypo...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Sun, Ling, Zhu, Wenwu, Zhao, Pengcheng, Wang, Qingjie, Fan, Baohan, Zhu, Yeqian, Lu, Yao, Chen, Qiushi, Zhang, Jian, Zhang, Fengxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442657/
https://ncbi.nlm.nih.gov/pubmed/32826854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02783-5
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