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QSAR-driven rational design of novel DNA methyltransferase 1 inhibitors
DNA methylation, an epigenetic modification, is mediated by DNA methyltransferases (DNMTs), a family of enzymes. Inhibitions of these enzymes are considered a promising strategy for the treatment of several diseases. In this study, a quantitative structure-activity relationship (QSAR) modeling was e...
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| Publicado no: | EXCLI J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Leibniz Research Centre for Working Environment and Human Factors
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7214779/ https://ncbi.nlm.nih.gov/pubmed/32398970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-1096 |
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