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Probing the origins of aromatase inhibitory activity of disubstituted coumarins via QSAR and molecular docking
This study investigated the quantitative structure-activity relationship (QSAR) of imidazole derivatives of 4,7-disubstituted coumarins as inhibitors of aromatase, a potential therapeutic protein target for the treatment of breast cancer. Herein, a series of 3,7- and 4,7-disubstituted coumarin deriv...
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| Publicado no: | EXCLI J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Leibniz Research Centre for Working Environment and Human Factors
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463968/ https://ncbi.nlm.nih.gov/pubmed/26417339 |
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