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Investigation of aromatase inhibitory activity of metal complexes of 8-hydroxyquinoline and uracil derivatives

PURPOSE: Estrogens play important roles in the pathogenesis and progression of breast cancer as well as estrogen-related diseases. Aromatase is a key enzyme in the rate-limiting step of estrogen production, in which its inhibition is one strategy for controlling estrogen levels to improve prognosis...

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Detalhes bibliográficos
Main Authors: Prachayasittikul, Veda, Pingaew, Ratchanok, Nantasenamat, Chanin, Prachayasittikul, Supaluk, Ruchirawat, Somsak, Prachayasittikul, Virapong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140444/
https://ncbi.nlm.nih.gov/pubmed/25152615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S67300
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