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Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking

Alzheimer’s disease (AD) is a chronic neurodegenerative disease which leads to the gradual loss of neuronal cells. Several hypotheses for AD exists (e.g., cholinergic, amyloid, tau hypotheses, etc.). As per the cholinergic hypothesis, the deficiency of choline is responsible for AD; therefore, the i...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Simeon, Saw, Anuwongcharoen, Nuttapat, Shoombuatong, Watshara, Malik, Aijaz Ahmad, Prachayasittikul, Virapong, Wikberg, Jarl E.S., Nantasenamat, Chanin
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991866/
https://ncbi.nlm.nih.gov/pubmed/27602288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2322
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