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Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking

Alzheimer’s disease (AD) is a chronic neurodegenerative disease which leads to the gradual loss of neuronal cells. Several hypotheses for AD exists (e.g., cholinergic, amyloid, tau hypotheses, etc.). As per the cholinergic hypothesis, the deficiency of choline is responsible for AD; therefore, the i...

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Bibliografische gegevens
Gepubliceerd in:PeerJ
Hoofdauteurs: Simeon, Saw, Anuwongcharoen, Nuttapat, Shoombuatong, Watshara, Malik, Aijaz Ahmad, Prachayasittikul, Virapong, Wikberg, Jarl E.S., Nantasenamat, Chanin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: PeerJ Inc. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991866/
https://ncbi.nlm.nih.gov/pubmed/27602288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2322
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