QSAR-driven rational design of novel DNA methyltransferase 1 inhibitors

DNA methylation, an epigenetic modification, is mediated by DNA methyltransferases (DNMTs), a family of enzymes. Inhibitions of these enzymes are considered a promising strategy for the treatment of several diseases. In this study, a quantitative structure-activity relationship (QSAR) modeling was e...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EXCLI J
Autori principali: Phanus-umporn, Chuleeporn, Prachayasittikul, Veda, Nantasenamat, Chanin, Prachayasittikul, Supaluk, Prachayasittikul, Virapong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Leibniz Research Centre for Working Environment and Human Factors 2020
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214779/
https://ncbi.nlm.nih.gov/pubmed/32398970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-1096
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi