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Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician’s perspective

OBJECTIVE: In this review, we have summarized the pharmacokinetics, pharmacodynamics and adverse effects of imatinib, dasatinib, nilotinib, bosutinib, ponatinib and radotinib with focus on pharmacogenomic studies with clinical end points. We have discussed the key phase 3 trials of tyrosine kinase i...

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Sparad:
Bibliografiska uppgifter
I publikationen:Daru
Huvudupphovsmän: Pushpam, Deepam, Bakhshi, Sameer
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214547/
https://ncbi.nlm.nih.gov/pubmed/31900888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-019-00321-z
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