A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes

Established cell culture systems have failed to accurately recapitulate key features of terminal erythroid maturation, hampering our ability to in vitro model and treat diseases with impaired erythropoiesis such as myelodysplastic syndromes with ring sideroblasts (MDS-RS). We developed an efficient...

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Pubblicato in:Leukemia
Autori principali: Elvarsdóttir, Edda María, Mortera-Blanco, Teresa, Dimitriou, Marios, Bouderlique, Thibault, Jansson, Monika, Hofman, Isabel Juliana F., Conte, Simona, Karimi, Mohsen, Sander, Birgitta, Douagi, Iyadh, Woll, Petter S., Hellström-Lindberg, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214248/
https://ncbi.nlm.nih.gov/pubmed/31375745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0532-7
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