A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes

Established cell culture systems have failed to accurately recapitulate key features of terminal erythroid maturation, hampering our ability to in vitro model and treat diseases with impaired erythropoiesis such as myelodysplastic syndromes with ring sideroblasts (MDS-RS). We developed an efficient...

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Vydáno v:Leukemia
Hlavní autoři: Elvarsdóttir, Edda María, Mortera-Blanco, Teresa, Dimitriou, Marios, Bouderlique, Thibault, Jansson, Monika, Hofman, Isabel Juliana F., Conte, Simona, Karimi, Mohsen, Sander, Birgitta, Douagi, Iyadh, Woll, Petter S., Hellström-Lindberg, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214248/
https://ncbi.nlm.nih.gov/pubmed/31375745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0532-7
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