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Hormonal suppression of stem cells inhibits symmetric cell division and gastric tumorigenesis
Cancer is believed to arise from stem cells, but mechanisms that limit the acquisition of mutations and tumor development have not been well-defined. We show that a +4 stem cell (SC) in the gastric antrum, marked by expression of Cck2r (a GPCR) and Delta-like ligand 1 (DLL1), is a label-retaining ce...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Stem Cell |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7214188/ https://ncbi.nlm.nih.gov/pubmed/32142681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.01.020 |
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