Reduced Sirtuin1 signalling exacerbates diabetic mice hindlimb ischaemia injury and inhibits the protective effect of a liver X receptor agonist

Diabetes mellitus causes endothelial dysfunction, which further exacerbates peripheral arterial disease (PAD). Improving endothelial function via reducing endothelial oxidative stress (OS) may be a promising therapy for diabetic PAD. Activation of liver X receptor (LXR) inhibits excessive OS and pro...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Fan, Wensi, Zhang, Ran, Han, Dong, Jiang, Zhenhua, Li, Shuang, Zhang, Jibin, Li, Yanhua, Wang, Yabin, Cao, Feng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214142/
https://ncbi.nlm.nih.gov/pubmed/32286000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15201
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