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scBatch: batch-effect correction of RNA-seq data through sample distance matrix adjustment

MOTIVATION: Batch effect is a frequent challenge in deep sequencing data analysis that can lead to misleading conclusions. Existing methods do not correct batch effects satisfactorily, especially with single-cell RNA sequencing (RNA-seq) data. RESULTS: We present scBatch, a numerical algorithm for b...

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Bibliografische gegevens
Gepubliceerd in:Bioinformatics
Hoofdauteurs: Fei, Teng, Yu, Tianwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214039/
https://ncbi.nlm.nih.gov/pubmed/32053185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa097
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