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Mitigating the adverse impact of batch effects in sample pattern detection

MOTIVATION: It is well known that batch effects exist in RNA-seq data and other profiling data. Although some methods do a good job adjusting for batch effects by modifying the data matrices, it is still difficult to remove the batch effects entirely. The remaining batch effect can cause artifacts i...

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Vydáno v:Bioinformatics
Hlavní autoři: Fei, Teng, Zhang, Tengjiao, Shi, Weiyang, Yu, Tianwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061843/
https://ncbi.nlm.nih.gov/pubmed/29506177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty117
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