SKI knockdown inhibits human melanoma tumor growth in vivo

The SKI protein represses the TGF-β tumor suppressor pathway by associating with the Smad transcription factors. SKI is upregulated in human malignant melanoma tumors in a disease-progression manner and its overexpression promotes proliferation and migration of melanoma cells in vitro. The mechanism...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Chen, Dahu, Lin, Qiushi, Box, Neil, Roop, Dennis, Ishii, Shunsuke, Matsuzaki, Koichi, Fang, Tao, Hornyak, Thomas J., Reed, Jon A, Stavnezer, Ed, Timchenko, Nikolai A., Medrano, Estela E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213764/
https://ncbi.nlm.nih.gov/pubmed/19845874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2009.00603.x
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