Pre-treatment with microRNA-181a Antagomir Prevents Loss of Parvalbumin Expression and Preserves Novel Object Recognition Following Mild Traumatic Brain Injury

Mild traumatic brain injury (mTBI) can result in permanent impairment in memory and learning and may be a precursor to other neurological sequelae. Clinical treatments to ameliorate the effects of mTBI are lacking. Inhibition of microRNA-181a (miR-181a) is protective in several models of cerebral in...

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Publicado no:Neuromolecular Med
Main Authors: Griffiths, Brian B., Sahbaie, Peyman, Rao, Anand, Arvola, Oiva, Xu, Lijun, Liang, Deyong, Ouyang, Yibing, Clark, David J., Giffard, Rona G., Stary, Creed M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213504/
https://ncbi.nlm.nih.gov/pubmed/30900118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-019-08532-y
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