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Post-stroke treatment with miR-181 antagomir reduces injury and improves long-term behavioral recovery in mice after focal cerebral ischemia

MiR-181 has deleterious effects on stroke outcome, and reducing miR-181a levels prior to middle cerebral artery occlusion (MCAO) was shown previously to be protective. Here we tested the effect of post-ischemic treatment with miR-181a antagomir by intracerebroventricular and intravenous routes of ad...

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Dades bibliogràfiques
Publicat a:Exp Neurol
Autors principals: Xu, Li-Jun, Ouyang, Yi-Bing, Xiong, Xiaoxing, Stary, Creed M, Giffard, Rona G
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324354/
https://ncbi.nlm.nih.gov/pubmed/25433215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.11.007
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