LPTO-03. IN-VITRO & IN-VIVO CULTURE OF PATIENT (PT) DERIVED CSF-CTCs IN LEPTOMENINGEAL DISEASE (LMDz) FROM MELANOMA TO IDENTIFY NOVEL TREATMENT STRATEGIES

BACKGROUND: Approximately 5% of melanoma pts develop LMDz. There are essentially no models of LMDz available for therapeutic development. Here we report, the in-vitro & in-vivo culturing of CSF-CTCs. METHODS: CSF-CTCs were detected by the Veridex CellSearch® System. Cell-free DNA and cell-associ...

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Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Law, Vincent, Evernden, Brittany, Kenchappa, Rajappa, Puskas, John, Caceres, Gisela, Ryzhova, Elena, Smalley, Inna, Etame, Arnold, Sahebjam, Solmaz, Magliocco, Anthony, Smalley, Keiran, Forsyth, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213446/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.026
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