RADI-11. NRG ONCOLOGY CC001: A PHASE III TRIAL OF HIPPOCAMPAL AVOIDANCE IN ADDITION TO WHOLE-BRAIN RADIOTHERAPY (WBRT) PLUS MEMANTINE TO PRESERVE NEUROCOGNITIVE FUNCTION IN PATIENTS WITH BRAIN METASTASES (BM)

BACKGROUND: NRG CC001, a phase III trial of WBRT+memantine (WBRT+M) with or without Hippocampal Avoidance (HA), sought to assess the neuro-protective effects of lowering the radiation dose received by the hippocampus. METHODS: Patients (pts) with brain metastases were stratified by RPA class and pri...

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Publicat a:Neurooncol Adv
Autors principals: Tomé, Wolfgang, Deshmukh, Snehal, Gondi, Vinai, Brown, Paul, Wefel, Jeffery, Armstrong, Terri, Bruner, Deborah, Bovi, Joseph, Robinson, Clifford, Khuntia, Deepak, Grosshans, David, Konski, Andre, Roberge, David, Kundapur, Vijayananda, Devisetty, Kiran, Shah, Sunjay, Usuki, Kenneth, Anderson, Bethany Marie, Mehta, Minesh, Kachnic, Lisa
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213360/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.104
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