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BSCI-03. T CELL EXHAUSTION SIGNATURES VARY BY TUMOR TYPE AND ARE INDEPENDENT OF INTRACRANIAL LOCATION

T-cell exhaustion is a hindrance to the efficacy of immune checkpoint blockade. This study is among the first to examine, and credential as bona fide, exhaustion among T cells infiltrating murine models of brain metastasis, including breast, lung, and melanoma cancers. Furthermore, this study demons...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Woroniecka, Karolina, Chongsathidkiet, Pakawat, Cui, Xiuyu, Dechant, Cosette, Wilkinson, Daniel, Fecci, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213120/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.002
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