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Exact Distribution of Linkage Disequilibrium in the Presence of Mutation, Selection, or Minor Allele Frequency Filtering

Linkage disequilibrium (LD), often expressed in terms of the squared correlation (r(2)) between allelic values at two loci, is an important concept in many branches of genetics and genomics. Genetic drift and recombination have opposite effects on LD, and thus r(2) will keep changing until the effec...

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Vydáno v:Front Genet
Hlavní autoři: Qu, Jiayi, Kachman, Stephen D., Garrick, Dorian, Fernando, Rohan L., Cheng, Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212447/
https://ncbi.nlm.nih.gov/pubmed/32425975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00362
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