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Exact Distribution of Linkage Disequilibrium in the Presence of Mutation, Selection, or Minor Allele Frequency Filtering

Linkage disequilibrium (LD), often expressed in terms of the squared correlation (r(2)) between allelic values at two loci, is an important concept in many branches of genetics and genomics. Genetic drift and recombination have opposite effects on LD, and thus r(2) will keep changing until the effec...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Qu, Jiayi, Kachman, Stephen D., Garrick, Dorian, Fernando, Rohan L., Cheng, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212447/
https://ncbi.nlm.nih.gov/pubmed/32425975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00362
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