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Thrombomodulin and the vascular endothelium: insights into functional, regulatory, and therapeutic aspects

Thrombomodulin (TM) is a 557-amino acid protein with a broad cell and tissue distribution consistent with its wide-ranging physiological roles. When expressed on the lumenal surface of vascular endothelial cells in both large vessels and capillaries, its primary function is to mediate endothelial th...

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Bibliographic Details
Published in:Am J Physiol Heart Circ Physiol
Main Authors: Martin, Fiona A., Murphy, Ronan P., Cummins, Philip M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212260/
https://ncbi.nlm.nih.gov/pubmed/23604713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00096.2013
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