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Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro.

Endotoxemia is frequently associated clinically with disseminated intravascular coagulation (DIC); however, the mechanism of endotoxin action in vivo is unclear. Modulation of tissue factor (TF) and thrombomodulin (TM) expression on the endothelial surface may be relevant pathophysiologic mechanisms...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Moore, K L, Andreoli, S P, Esmon, N L, Esmon, C T, Bang, N U
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112772
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