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Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

INTRODUCTION: Alveolar macrophages (AMs) are critical in the development of lung adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations. Whether interstitial macrophages (IMs) are also involved in lung tumorigenesis is still unclear. Thus, the aim of this study is to evaluate the...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Alikhanyan, Kristina, Chen, Yuanyuan, Kraut, Simone, Sotillo, Rocio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212197/
https://ncbi.nlm.nih.gov/pubmed/32125091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.293
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