Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

INTRODUCTION: Alveolar macrophages (AMs) are critical in the development of lung adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations. Whether interstitial macrophages (IMs) are also involved in lung tumorigenesis is still unclear. Thus, the aim of this study is to evaluate the...

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Veröffentlicht in:Immun Inflamm Dis
Hauptverfasser: Alikhanyan, Kristina, Chen, Yuanyuan, Kraut, Simone, Sotillo, Rocio
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212197/
https://ncbi.nlm.nih.gov/pubmed/32125091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.293
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