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Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

INTRODUCTION: Alveolar macrophages (AMs) are critical in the development of lung adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations. Whether interstitial macrophages (IMs) are also involved in lung tumorigenesis is still unclear. Thus, the aim of this study is to evaluate the...

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Publicat a:Immun Inflamm Dis
Autors principals: Alikhanyan, Kristina, Chen, Yuanyuan, Kraut, Simone, Sotillo, Rocio
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212197/
https://ncbi.nlm.nih.gov/pubmed/32125091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.293
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