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Anhydrous hydrogen fluoride cleavage in Boc solid phase peptide synthesis
Solid phase peptide synthesis using tert-butyloxycarbonyl/benzyl chemistry (Boc-SPPS) is important for producing peptides for fundamental research as well as for clinical use. During Boc-SPPS, liquid anhydrous hydrogen fluoride (HF) is used to remove the sidechain protecting groups of the assembled...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7212049/ https://ncbi.nlm.nih.gov/pubmed/31879918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0227-0_4 |
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