A viral toolkit for recording transcription factor–DNA interactions in live mouse tissues

Transcription factors (TFs) enact precise regulation of gene expression through site-specific, genome-wide binding. Common methods for TF-occupancy profiling, such as chromatin immunoprecipitation, are limited by requirement of TF-specific antibodies and provide only end-point snapshots of TF bindin...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Cammack, Alexander J., Moudgil, Arnav, Chen, Jiayang, Vasek, Michael J., Shabsovich, Mark, McCullough, Katherine, Yen, Allen, Lagunas, Tomas, Maloney, Susan E., He, June, Chen, Xuhua, Hooda, Misha, Wilkinson, Michael N., Miller, Timothy M., Mitra, Robi D., Dougherty, Joseph D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211997/
https://ncbi.nlm.nih.gov/pubmed/32300008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918241117
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