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APOBEC3A loop 1 is a determinant for ssDNA binding and deamination
The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3 or A3) family of proteins functions in the innate immune system. The A3 proteins are interferon inducible and hypermutate deoxycytidine to deoxyuridine in foreign single-stranded DNA (ssDNA). However, this deaminase activ...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7211764/ https://ncbi.nlm.nih.gov/pubmed/31448897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00394 |
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