Suppression of miR-330-3p alleviates DSS-induced ulcerative colitis and apoptosis by upregulating the endoplasmic reticulum stress components XBP1

BACKGROUND: This study aimed to explore the biological activities of miR-330-3p in dextan sulphate sodium (DSS)-induced ulcerative colitis and apoptosis and the direct target of miR-330-3p in this process. HT-29 cells and male C57BL/6 mice were used to examine the function of miR-330-3p in vitro and...

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Bibliographische Detailangaben
Veröffentlicht in:Hereditas
Hauptverfasser: Chen, Qifeng, Fang, Xiaoming, Yao, Ning, Wu, Fang, Xu, Biao, Chen, Zhengguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211341/
https://ncbi.nlm.nih.gov/pubmed/32386518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41065-020-00135-z
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