Upregulation of miR-665 promotes apoptosis and colitis in inflammatory bowel disease by repressing the endoplasmic reticulum stress components XBP1 and ORMDL3

MicroRNAs are critical post-transcriptional regulators of gene expression and key mediators of pathophysiology of inflammatory bowel disease (IBD). This study is aimed to study the role of miR-665 in the progression of IBD. Real-time PCR analysis was used to determine miR-665 expression in 89 freshl...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Manying, Zhang, Shenghong, Qiu, Yun, He, Yao, Chen, Baili, Mao, Ren, Cui, Yi, Zeng, Zhirong, Chen, Minhu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386569/
https://ncbi.nlm.nih.gov/pubmed/28333149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.76
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