Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis

This study investigates the role of NLRP3 inflammasome and its main effector Caspase-1 in inflammation and alveolar bone resorption associated with periodontitis. Heat-killed Aggregatibacter actinomycetemcomitans (Aa) was injected 3x/week (4 weeks) into gingival tissues of wild-type (WT), Nlrp3-KO a...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Rocha, Fernanda R G., Delitto, Andrea E., de Souza, Joao A. Chaves, González-Maldonado, Laura A., Wallet, Shannon M., Rossa Junior, Carlos
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210885/
https://ncbi.nlm.nih.gov/pubmed/32385413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64685-y
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki