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The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy
Lineage-specific genetic programs rely on cell-restricted super-enhancers, which are platforms for high-density transcription factor occupation. It is not known whether super-enhancers synergize specifically with their native promoters or provide autonomous and independent regulatory platforms. Here...
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| Опубликовано в: : | Exp Mol Med |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7210877/ https://ncbi.nlm.nih.gov/pubmed/32321991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0425-x |
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