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AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo
Cell-selective gene expression comprises a critical element of many adeno-associated virus (AAV) vector-based gene therapies, and to date achieving this goal has focused on AAV capsid engineering, cell-specific promoters, or cell-specific enhancers. Recently, we discovered that the capsid of AAV9 ex...
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| Udgivet i: | Mol Ther |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Gene & Cell Therapy
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7210720/ https://ncbi.nlm.nih.gov/pubmed/32213322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.03.007 |
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