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Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus

Tumor-targeting oncolytic viruses such as vaccinia virus (VV) are attractive cancer therapeutic agents that act through multiple mechanisms to provoke both tumor lysis and anti-tumor immune responses. However, delivery of these agents remains restricted to intra-tumoral administration, which prevent...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther
मुख्य लेखकों: Ferguson, Mark S., Chard Dunmall, Louisa S., Gangeswaran, Rathi, Marelli, Giulia, Tysome, James R., Burns, Emily, Whitehead, Maria A., Aksoy, Ezra, Alusi, Ghassan, Hiley, Crispin, Ahmed, Jay, Vanhaesebroeck, Bart, Lemoine, Nicholas R., Wang, Yaohe
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Gene & Cell Therapy 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210704/
https://ncbi.nlm.nih.gov/pubmed/32145202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.02.017
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