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Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours
Hypoxia contributes to the aggressive and treatment-resistant phenotype of pancreatic ductal adenocarcinoma (PDAC). Oncolytic vaccinia virus has potential as an anti-tumour agent but the ability to lyse hypoxic tumour cells is vital for clinical efficacy. We hypothesised that unique aspects of the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875103/ https://ncbi.nlm.nih.gov/pubmed/19890355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.132 |
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