Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension

The development of hypertension is associated with mitochondrial redox balance disruptions. NADP(+)-dependent isocitrate dehydrogenase 2 (IDH2) plays an important role in the maintenance of mitochondrial redox balance by producing mitochondrial NADPH, which is an essential cofactor in the reduction...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Noh, Mi Ra, Kong, Min Jung, Han, Sang Jun, Kim, Jee In, Park, Kwon Moo
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210593/
https://ncbi.nlm.nih.gov/pubmed/32388270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101548
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