SAT-303 3D Mapping of the Human Growth Hormone Locus Identifies Putative Regulatory Hubs for Genes Involved in Cellular Signalling and Cancer-Related Pathways

Growth hormone (GH) is a peptide hormone predominantly produced in the pituitary that is crucial for normal growth and metabolism. Downstream effects of GH are mediated through binding to the GH receptor (GHR) and consequent activation of key signalling cascades including JAK-STAT, MAPK, PI3K-Akt an...

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Vydáno v:J Endocr Soc
Hlavní autoři: Jain, Lekha, Fadason, Tayaza, Schierding, William, Vickers, Mark Hedley, O’Sullivan, Justin M, Perry, Jo Kate
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Neuroendocrinology and Pituitary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209482/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.344
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