Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs

The mechanisms that underlie the association between obesity and type 2 diabetes are not fully understood. Here, we investigated the role of the 3D genome organization in the pathogeneses of obesity and type-2 diabetes. We interpreted the combined and differential impacts of 196 diabetes and 390 obe...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Fadason, Tayaza, Ekblad, Cameron, Ingram, John R., Schierding, William S., O'Sullivan, Justin M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645506/
https://ncbi.nlm.nih.gov/pubmed/29081791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00150
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