SUN-667 Hyperinsulinemia Suppresses Hepatic Autophagy at Late Sepsis in an mTOR-Dependent Transcriptional Regulation

Autophagy transiently occurs in the liver at early stage, while autophagy suppression associated with liver failure occurs at late stage in a CLP (cecal ligation and puncture) model of sepsis. However, the factors that cause autophagy suppression at late sepsis remain unknown. Hyperinsulinemia is ob...

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Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Hsu, Chin, Wang, Li-Fang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Diabetes Mellitus and Glucose Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209453/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.845
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