SUN-211 Active Steroid Hormone Synthesis Renders Adrenocortical Cells Highly Susceptible to Type II Ferroptosis Induction

Context: Cell death in the adrenal cortex is ill understood but of high clinical relevance. Resistance of adrenocortical carcinoma (ACC) to current treatment with mitotane and chemotherapy calls for an improved understanding of adrenal cortical cell death processes. Ferroptosis is an iron-dependent...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Weigand, Isabel, Schreiner, Jochen, Roehrig, Florian, Sun, Na, Laura-Sophie, Landwehr, Urlaub, Hanna, Kiseljak-Vassiliades, Katja, Wierman, Margaret E, Angeli, José Pedro Friedmann, Walch, Axel K, Sbiera, Silviu, Fassnacht, Martin, Kroiss, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Adrenal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209342/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1931
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