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Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma

BACKGROUND: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy. Tumor-related glucocorticoid excess is present in ~60% of patients and associated with particularly poor prognosis. Results of first clinical trials using immune checkpoint inhibitors were heterogeneous. Here we characterize...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Landwehr, Laura-Sophie, Altieri, Barbara, Schreiner, Jochen, Sbiera, Iuliu, Weigand, Isabel, Kroiss, Matthias, Fassnacht, Martin, Sbiera, Silviu
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264832/
https://ncbi.nlm.nih.gov/pubmed/32474412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000469
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