Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction

Conditions of impaired adrenal function and tissue destruction, such as in Addison’s disease, and treatment resistance of adrenocortical carcinoma (ACC) necessitate improved understanding of the pathophysiology of adrenal cell death. Due to relevant oxidative processes in the adrenal cortex, our stu...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Weigand, Isabel, Schreiner, Jochen, Röhrig, Florian, Sun, Na, Landwehr, Laura-Sophie, Urlaub, Hanna, Kendl, Sabine, Kiseljak-Vassiliades, Katja, Wierman, Margaret E., Angeli, José Pedro Friedmann, Walch, Axel, Sbiera, Silviu, Fassnacht, Martin, Kroiss, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078189/
https://ncbi.nlm.nih.gov/pubmed/32184394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2385-4
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