OR32-03 Serum Cell-Free Methylation-Based Signatures Distinguishes Pituitary Tumors According to Functional Status and from Other Neoplasia: A Liquid Biopsy Approach

BACKGROUND: Several reports have indicated that distinct epigenomic patterns of pituitary tumors (PT), specifically DNA methylation, distinguish these tumor tissues according to their functionality and could be involved in their pathogenesis. Thus far, molecular diagnosis and classification criteria...

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Pubblicato in:J Endocr Soc
Autori principali: Wells, Michael, Asmaro, Karam P, Sabedot, Thais S, Mosella, Maritza S, Malta, PharmD, Tathiane M, Nelson, Kevin, Snyder, James, deCarvalho, Ana, Mukherjee, Abir, Chitale, Dan, Robin, Adam, Rosenblum, Mark L, Mikkelsen, Tom, Poisson, Laila, Lee, Ian, Walbert, Tobias, Bhan, Arti, Kalkanis, Steven, Rock, Jack, Noushmehr, Houtan, Castro, Ana Valeria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Neuroendocrinology and Pituitary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209178/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.542
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