MON-033 Androgen Increases the Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

Polycystic ovarian syndrome (PCOS) is associated with hyperandrogenism. Previously we found that androgen activated endoplasmic reticulum (ER) stress in granulosa cells of antral follicles in PCOS, contributing to ovarian fibrosis (1) and growth arrest of antral follicles (2). In addition, recent st...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Azhary, Jerilee Mariam Khong, Harada, Miyuki, Takahashi, Nozomi, Hirota, Yasushi, Koga, Kaori, Osuga, Yutaka, Hiraike, Osamu, Kunitomi, Chisato
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Reproductive Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209029/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.182
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