MON-033 Androgen Increases the Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

Polycystic ovarian syndrome (PCOS) is associated with hyperandrogenism. Previously we found that androgen activated endoplasmic reticulum (ER) stress in granulosa cells of antral follicles in PCOS, contributing to ovarian fibrosis (1) and growth arrest of antral follicles (2). In addition, recent st...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Endocr Soc
Hlavní autoři: Azhary, Jerilee Mariam Khong, Harada, Miyuki, Takahashi, Nozomi, Hirota, Yasushi, Koga, Kaori, Osuga, Yutaka, Hiraike, Osamu, Kunitomi, Chisato
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Reproductive Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209029/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.182
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky