MON-033 Androgen Increases the Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

Polycystic ovarian syndrome (PCOS) is associated with hyperandrogenism. Previously we found that androgen activated endoplasmic reticulum (ER) stress in granulosa cells of antral follicles in PCOS, contributing to ovarian fibrosis (1) and growth arrest of antral follicles (2). In addition, recent st...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Azhary, Jerilee Mariam Khong, Harada, Miyuki, Takahashi, Nozomi, Hirota, Yasushi, Koga, Kaori, Osuga, Yutaka, Hiraike, Osamu, Kunitomi, Chisato
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Reproductive Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209029/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.182
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